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Icaritin CAS No.: 118525-40-9 High Purity 98% Factory direct

Icaritin CAS No.: 118525-40-9 High Purity 98% Factory direct

英文名:Icaritin

彩票大赢家CASHAO:CAS No.: 118525-40-

GUI  GE:98%

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English Name: Icaritin

CAS No.: 118525-40-9

Synonym: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one

Molecular Formula: C21H20O6

Molecular Weight: 368.38

MDL number MFCD2242251

PubChem Substance ID 329825547

Molecular structure:

 

 

Appearance: yellow powder

Purity: ≥98%

Identification methods: Mass, NMR

Analysis method: HPLC-DAD or/and HPLC-ELSD

Extraction Source: Epimedium spp.

Biochem/physiol Actions:

Icaritin is a component of Epimedium flavonoid isolated from Herba Epimedii, which enhances osteoblastic differentiation of mesenchymal stem cells (MSCs) while it inhibits adipogenic differentiation of MSCs by inhibiting PPAR-g pathway. Icaritin has no effect on MSCs proliferation. Also, icaritin potently inhibits chronic myeloid leukemia (CML) and breast cancer cells proliferation most likely by modulation of MAPK/ERK/JNK and JAK2/STAT3 /AKT signaling. As other flavonoids, icaritin may exert estrogen-like activities.

Icaritin enhances osteoblastic differentiation of mesenchymal stem cells (MSCs). It may have estrogen-like activities.

Usage: For the determination and identification, pharmacological experiments.

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